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Oxidative stress has been highlighted as an important contributor to both apoptosis [201] and eryptosis [202]

Both play vital roles in healthy ageing, but they address different aspects of the process

Risk factors for COVID-19 include cardiovascular disease and diabetes, and such high-risk groups exhibit common metabolic features of low levels of Gln, NAD + , and overproduction of hyaluronic acid (HA)

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FIGURE 7 Conclusion and perspectives As a significant kind of PCD, ferroptosis can be triggered pharmacologically or genetically