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The signs and symptoms of methylmalonic acidemia with homocystinuria worsen over time and can result in life-threatening complications if not properly treated
Patients who are unable to tolerate the 3-mg dose should stop treatment, as should patients who do not lose 4% of their baseline body weight after four months
Schippling et al., 2000
276 In its resting state, STING resides in the ER, where it interacts with the Ca 2+ -sensing transmembrane protein stromal interaction molecule 1 (STIM1) and the ER Ca 2+ pump ATPase sarcoplasmic/endoplasmic reticulum Ca 2+ transporting 2 (ATP2A2, also known as SERCA2)
