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Many patients have taken these medications for years, often at higher doses, and new concerns are emerging about chronic gastrointestinal, neurological, pancreatic, renal, and hormonal effects

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Vlachogiannakos J, Saveriadis AS, Viazis N et al (2009) Intestinal decontamination improves liver haemodynamics in patients with alcohol-related decompensated cirrhosis