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Sulforaphane, an isothiocyanate derived from broccoli and broccoli sprouts, is the most potent naturally occurring inducer of Nrf2

was supported by an International Atherosclerosis Society Fellowship

Notably, ROS may contribute to oxidized protein damage within the stratum corneum, thereby disrupting barrier function and exacerbating AD ( 3.2.2 Advanced glycation end- products Advanced glycation end-products (AGEs) and AOPPs share structural similarities and exert comparable biological effects

This same technique promotes melanocyte activity and aids in localized repigmentation, and it is commonly used in conjunction with topical treatments