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Although there were only marginal increases in intracellular GSSG levels ( P = 0.064), IL-13 increased extracellular (apical supernatant) GSSG ( P = 0.009), while lowering both GSH ( P = 0.012) and GSH:GSSG ( P = 0.006
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doi: 10.3920/BM2017.0009 Summary Keywords myopia, gut microbiota, Mendelian randomization, full-length 16S rRNA gene sequencing, Bifidobacterium Citation Tang G, Han Y, Gong X, Wang X, Li J, Zhang J, Wang J, Song J and Bi H (2025) Potential protective role of Bifidobacteria in myopia prevention: evidence from full-length 16S rRNA sequencing and bidirectional Mendelian randomization analysis
Future studies are warranted to investigate whether DAP, reuterin, and 5-MIAA can reach the ovarian follicle and modulate ferroptosis pathways in granulosa cells, which may have important implications for understanding PCOS-associated follicular dysfunction
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