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Estas terapias han demostrado eficacia al disminuir la concentracin de HbA1c, glucemia plasmtica y glucemia postprandial, mejorando el control glucmico de estos pacientes, sin embargo, los efectos en la mortalidad cardiovascular difieren en los dos grupos farmacolgicos presentes donde la liraglutida, un agonista del receptor GLP-1 (GLP-1R), demostr recientemente en el ensayo clnico denominado LEADER un beneficio cardiovascular, que es equivalente al recientemente constatado por los inhibidores del SGLT-2 4
Common gastrointestinal side effects (nausea, vomiting, reduced appetite) may indirectly contribute to irritability or discomfort
Comparison of the results between men and women was, however, not conducted as this was not considered meaningful because of the limited sample size
For example, while acetaminophen shows a delay in reaching peak concentration, its overall bioavailability remains unchanged
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