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These modifications preserve the peptides structural integrity, extending its half-life to approximately 30 minutes
doi:10.1017/s0029665100000847 Ghezzi P
Cost and coverage frequently override the efficacy comparison entirely
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While the specific mechanism causing the effects on the gastrointestinal tract are not fully elucidated, studies suggest GLP-1 and its analogues likely exert effects on the vagus nerve and inhibit cholinergic neurotransmission in the gastrointestinal system to prevent movement of the intestine
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