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Myopathy, lactic acidosis and sideroblastic anemia Myopathy, lactic acidosis, and sideroblastic anemia (MLASA) is an autosomal recessive mitochondrial disorder affecting skeletal muscle and bone marrow, characterized by mitochondrial myopathy, lactic acidosis, and sideroblastic anemia

Titration protocols therefore hold a dose until nausea and other gastrointestinal effects settle rather than escalating on a fixed target date

These range from IV (intravenous) glutathione to different oral forms of glutathione to transdermal

Ramasamy R, Masterson TA, Best JC, et al

This is particularly beneficial for those with a history of gastrointestinal issues