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Acknowledgements This work was supported by the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education (2018R1A6A1A03023718 and 2020R1I1A1A01067423) and by the NRF grant funded by the Korean government (MSIT) (2020M3E5E2040282)
the present invention is related to a process for producing semapeptide, the process comprising the steps of: a) culturing a host cell comprising a nucleotide sequence encoding of Formula (II) under suitable conditions for expression, insoluble tag is a nucleotide sequence of Alanine -Valine SUBSTITUTE SHEETS (RULE 26) b) recovering semapeptide, wherein semapeptide amino acid sequence is Glu-Gly-Thr-Phe- Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg- Gly-Arg-Gly
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doi: 10.2147/IJN.S484838 75 LvYLiWLiaoWJiangHLiuYCaoJet al
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