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Their inclusion does not represent endorsement of any research product, supplier, personal use, treatment claim or commercial statement discussed in this article
2 For a 505(b)(2) sponsor, these new indications represent a value continuum where they can repurpose an established molecule for a specialized population with much lower risk
These CVOT findings are supported by a real-world study performed in over 3 million patients with T2DM from the United States, in which patients treated with SGLT2is did not have a higher risk of any or lower amputation compared with incretins or other glucose-lowering agents [77]
Headache: The Journal of Head and Face Pain, 60(3), 415-423
