and the interstitium, which can cause acute interstitial nephritis (AIN)
More significantly, MOTS-c administration shifted the trajectory of age-related metabolic decline, indicating that the peptide's benefits are not limited to preventing dysfunction in young animals but can partially reverse established decline [2]
00:12:26 Craig Williams Yeah, Ill add, Sara, that as far as being concerned that the drug itself has like neurologic causes or toxicities, I also have not appreciated that
No participants withdrew from any trial due to tolerability issues, indicating that even when side effects occurred, they were sufficiently manageable that participants chose to continue treatment
The study did not determine the reason patients were prescribed these medications and the severity of the strokes that patients experienced could not be assessed, which may have affected the outcomes