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GH peak/insulin-like growth factor-1 (IGF-1) were also significantly reduced in severe ME/CFS patients compared to controls and ME/CFS patients with mild disease

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EBV infection activates the p62-Keap1-NRF2 pathway and upregulates GPX4 expression in NPC cells The cystine transporter SLC7A11 and peroxidase GPX4 are key effectors of ferroptosis [22]