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This explains why topical applications achieve far lower tissue concentrations than injection
But they carry significant limitations
Some genetic changes, like in the MTHFR gene, can affect how Vitamin B12 is used in the body
The peptide is a modified fragment of the growth hormone where the last 16 amino acids (176-191) have been reproduced as a specific peptide, called GH Fragment 176-191 or simply AOD 9604
Vitamin B12 deficiency is primarily caused by autoimmune pernicious anemia, dietary restrictions such as vegetarian or vegan diets, and medical conditions that interfere with absorption such as celiac and Crohns disease
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