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While it does activate GLP-1 receptors like semaglutide, it has five times stronger affinity for GIP receptors, creating a metabolic signal your body doesn't get from GLP-1 medications alone
The authors suggested other factors were coming into play, possibly reductions in blood sugar levels or inflammation or some other direct effect on the cardiovascular system
Tirzepatide is often considered when there is more weight to lose, when prediabetes or type 2 diabetes is present, or when previous attempts with other medications did not give enough change
Fisher at Medical Weight Loss to discuss whether GLP-1 medication injections are right for you.
Pharmacologic approaches to glycemic treatment: Standards of Medical Care in Diabetes-2022
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