The renal or extrarenal expression of 1--hydroxylase (CYP27B1) enzymatic action converts 25(OH)VD 3 to an active metabolite 1,25-dihydroxy vitamin D 3 (1,25(OH) 2 VD 3) 13
By utilizing fats for energy production, this supplement helps conserve glycogen and delay the buildup of lactic acid, which in turn reduces muscle fatigue and extends the horse's ability to perform at peak levels
Athletes and active individuals often notice that consistent supplementation helps their body bounce back quicker
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In the same study, the human colon carcinoma cell line HCT116 was revealed to be less sensitive to the bleomycin treatment, in line with the very low expression of CT2 and with the metabolism based on glycolysis rather than on FAO (Aouida et al., 2010)