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One of the purported mechanisms responsible for these changes is that the additives in UPF may interact with the striatum and hippocampus, which are known to assess the local calorie content, food taste and flavor (119, 120)

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Ionomycin significantly increased PS exposure in all conditions when compared to the DMSO control: Ringer (2.4% to 24%, p =0.0004), Ringer+Albumax (0.72% to 22%, p =0.0005), iRPMI (0.63% to 23%, p =0.0003) and iRPMI+Albumax (0.43% to 15%, p =0.0329)

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