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According to a recent press release, tirzepatide was non-inferior to dulaglutide, an agent with proven cardiovascular prevention benefits, in preventing MACE-3, defined as cardiovascular death, nonfatal heart attack, or nonfatal stroke

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For practical research use, the twice-weekly dosing schedule accounts for the short half-life while still maintaining therapeutic benefit through the lasting immunological changes each dose initiates

Another may struggle with side effects that make intimacy less appealing

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