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Jennifer Hardy May 21, 2025 4 min read If you're thinking about starting a GLP-1 medication for obesity, like Wegovy or Zepbound, youve probably started researching what has to change, especially when it comes to food and drinks

At present, there are growing concerns around GLP1 receptor agonist-based therapeutics, in particular their association with loss of lean body mass

In the case of tamoxifen, its primary function involves inhibiting ERs in breast tissue while having minimal effects elsewhere

Success rates still depend heavily on consistency, healthy eating, movement, sleep, and long term lifestyle changes

4.4 Oxyntomodulin and natural dual agonism Oxyntomodulin, a peptide derived from the proglucagon gene alongside GLP-1 and glucagon, provides a compelling example of endogenous polypharmacology