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In 2023, Genentech reported results from the Phase III OCARINA II study, which validated that the new 10-minute subcutaneous injection form of Ocrevus maintained efficacy comparable to the intravenous form in managing MRI lesion activity and B-cell depletion over 24 weeks

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Progress Tracking Tracking weekly is the most reliable way to assess whether a protocol is working, particularly given the delayed response timeline

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Administration discipline The commonly described route in dosage guides is subcutaneous injection , and that matters because route changes can alter how a protocol behaves in practice