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In a population pharmacokinetic analysis of four clinical trials, the mean semaglutide plasma concentration was estimated at 15.3 nM with 0.5 mg/week of semaglutide and 30.6 nM with 1.0 mg/week of semaglutide in the blood samples collected from week 4 to week 56 of treatment (98)

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For healthcare professionals , understanding the peak timing is relevant when: Assessing side effects : gastrointestinal symptoms may be more pronounced in the first 13 days post-injection when plasma levels are rising

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