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Unlike in the structures of R1881- and DHT-bound AR, T877 is not involved in hydrogen bonding (Figure 7D), which may explain the lower binding affinity of bicalutamide compared with R1881 or DHT

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Then, the RAW264.7 cells were lysed using RIPA lysis buffer supplemented with 1 mM phenylmethanesulfonyl fluoride (PMSF)

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= Trasfus

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Global burden of heart failure: a comprehensive and updated review of epidemiology

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