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To investigate the ability to generate a therapeutic effect, the multicellular tumor spheroids were treated with Ru(II)-OH, NP2, or NP4 (10 M Ru) in a 1% or 21% O 2 atmosphere and afterward incubated with a cell live or death stain
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S29 and S30, for 4T1 cells, treatment with Fer-1 rescued NSBSO-induced cell death by 42.13%, whereas treatment with Fer-1 did not markedly alleviate the NSBSO-induced B16 cells death
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