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handle per standard laboratory practice

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Adding epinephrine (often 1:100,000) to lidocaine (2% or 1% solution) can prolong the duration and reduce bleeding, but pre-mixed 1% vials usually do not contain epinephrine, so an epinephrine ampule must be added separately if needed

The use of ultrasound-guided injections in the study ensured precise delivery of the treatment into the small rabbit knee joint, improving the accuracy and consistency of the intervention