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if neurological involvement is present, maintenance is every two months Oral therapy is generally not appropriate where absorption is impaired (e.g., pernicious anaemia), as adequate levels cannot be reliably achieved Because B12 is water-soluble and any excess beyond hepatic storage capacity is excreted in the urine, it has a low toxicity profile

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The most commonly reported effects are mild injection-site irritation, short-term fatigue during TB-500 loading, and occasional headache

Pain levels decrease during both rest and activity

The lack of vitamin B12 in your diet may prevent your body from obtaining the necessary energy it requires to function