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doi: 10.1016/j.taap.2024.116883 125 ShafiSKhuranaNGuptaJ
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Pesquisa sobre reorganizao da matriz extracelular
Some portion of intranasally administered peptides may reach the central nervous system through the olfactory pathway, bypassing the blood-brain barrier
After derivatization with 10 l of 5 mM 7-diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (Sigma-Aldrich) at room temperature for 10 min, the maleimide ring was cleaved by addition of 30 l of 50 mM ammonium formate (Sigma-Aldrich) pH 4.2 at room temperature for another 30 min
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