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Topical and microinfusion-delivered PDRN is the newer application, with literature growing rapidly since 2020
10.1161/CIRCRESAHA.117.311401 23 GharagozlooP.Gutirrez-AdnA.ChamprouxA.NoblancA.KocerA.CalleA.et al (2016)
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Modulates gut microbiota composition, increasing shortchain fatty acids that stimulate vagal afferents, dampening anxiety and improving mood
Ex vivo tissue constructs assessing angiogenic factor expression, wound closure kinetics, and structural remodeling under controlled copper availability
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