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HTCS is a cytoplasmic membrane-spanning protein that comprises all domains of a classical two-component system in one polypeptide (N-terminal extracellular sensor, cytoplasmic histidine kinase, and response regulator)

KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease

Patients with DM may encounter thirst, frequent urination, weight loss, and other symptoms

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Clinical research highlights that oestrogen loss actually reduces the bodys natural production of GLP-1, the hormone responsible for signaling satiety