Like many other stress responsive transcription factors, NRF2 is mainly regulated at the level of protein stability by a variety of proteins
As newer incretin therapies continue to emerge, clinicians will likely gain additional tools for addressing diminished response to GLP-1 medications
Kevin Ritzenthaler, DCBCN, diplomate in clinical nutrition at Innovative Health in Weston, Wisconsin, the answer may be yes through a clinically researched supplement called Calocurb Clinical by Ortho Molecular Products
These may include nausea, reduced appetite, early fullness, constipation, diarrhea, bloating, burping, reflux, and abdominal discomfort
Knowing when to adjust your dose If side effects remain severe after two weeks at a given dose level, do not escalate further until they become manageable