These are not minor observations
There's a small incidence of anaphylaxis using IV iron but most commonly we see a range of "hypersensitivity reactions" with intravenous iron which include, but are not limited to the following: hives, rashes, joint swelling and pain, fever, headache, chills flu-like symptoms, abdominal pain, diarrhea and constipation as well as muscle pain and cramping
In particular, appropriately timed light exposure is a powerful synchronizer for the SCN: morning daylight can help anchor the phase of the circadian clock, counteracting the tendency for phase advance, while minimizing bright light at night, especially blue-enriched light from screens, prevents melatonin suppression and preserves sleep quality (Voiculescu et al., 2016)
Oxidative stress in ischemia/reperfusion injuries following acute ischemic stroke
Mancuso, C., Bonsignore, A., Di Stasio, E., Mordente, A