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One such peptide in the tissues is Epithalamin, naturally produced in the pineal gland
doi: 10.1210/me.2002-0072 162 FaasMBoumanAMoesaHHeinemanMJde LeijLSchuilingG
As with all research peptides, the goal is to build a data set that can either justify more formal studies or reveal that the compound is not suitable for future development
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Why this matters: Tirzepatide alone already very powerful (15-22%) May already be optimizing GIP/GLP-1 pathways maximally Adding amylin might only add 2-5% more weight loss But could significantly increase side effects Risk-benefit ratio unknown Contrast with CagriSema: CagriSema: Extensively studied, Phase 3 trials, known safety Tirzepatide + cagrilintide: Zero studies, no safety data, speculative Learn about evidence-based approaches at SeekPeptides - explore best peptides for weight loss and best peptide stack for weight loss
