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They induce the expression of inflammation-related genes, including CCL2 and CCL7, which enhance macrophage recruitment and chemotaxis (105)
Areas of investigation include: Endothelial function Microcirculatory signaling Platelet aggregation pathways Vascular homeostasis Nitric oxide production mechanisms These research models provide insight into endothelial biology and vascular signaling networks
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SPR analysis of macrocycle The binding constants of the macrocycles to the Met ectodomain were determined by SPR analysis using a Biacore T200 machine (GE Healthcare)
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