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They are released from gut endocrine cells and potentiate meal-stimulated insulin secretion
Hemolytic conditions are associated with rupture of cell membranes and liberation of hemoglobin, its derivatives like methemoglobin or ferrylhemoglobin, heme, and other erythrocyte-derived molecules like ATP, IL-33, or HSP70 [62]
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And muscle is metabolically expensive tissue
Morris et al., 2012
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