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Retatrutide binds to the GLP-1, GIP, and glucagon receptors at the same time, triggering a chain of effects: GLP-1 (Glucagon-Like Peptide-1) receptor: suppresses appetite and slows digestion
Endnotes: The efficacy estimand represents efficacy had all randomized participants remained on study intervention (with possible dose interruptions and modifications) without initiating prohibited weight management treatments (and glycemic rescue therapy for glycemic endpoints only)
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