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The breadth of DSIPs biological activity spanning sleep regulation, stress modulation, pain processing, antioxidant defence, and neuroprotection has led some researchers to characterise it as an adaptogenic peptide: one that supports homeostatic balance across multiple physiological systems rather than acting on a single discrete target

B12s role in melatonin production, a hormone responsible for regulating sleep, is believed to be significant

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

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Nov 10 2004;292(18):2243-2248