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A large proportion of patients are difficult to detect because the symptoms of TBI are more consistent with those of PTH, with a wide variation in diagnosis, with incidence rates ranging from 0.7% to 51.4% (Kishore et al., 1978)
Journal of physiology and pharmacology: an official journal of the Polish Physiological Society, 60 Suppl 7 , 115122
They are intentionally started at a low dose to support comfort and safety
In October 2023, A Research Study to See How Semaglutide Works Compared to Placebo in People with Type 2 Diabetes and Chronic Kidney Disease (FLOW) trial assessing the effect of semaglutide versus placebo on the progression of renal impairment in people with T2DM and chronic kidney disease was stopped prematurely due to results of an interim analysis showing significant efficacy of semaglutide with full results due to be released in the first half of 2024 [39]
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