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This naturally occurring substance is found in all mammalian tissues, especially striated muscle, and is required in energy metabolism, such as the oxidation of fatty acids, facilitating the aerobic metabolism of carbohydrates, and enhancing the excretion of certain organic acids

In the study by Kittipornkul et al

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European Study Group on Growth Hormone Treatment in Children with Nephropathic Cystinosis (2001) Long-term treatment with growth hormone in short children with nephropathic cystinosis

The altered physiology of adipose tissue in obesity releases metabolic substrates contributing to tumor cells proliferation, invasion, and metastasis