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Clinical trials so far have shown that injectable GLP-1 drugs, such as Wegovy and Zepbound, remain more effective, particularly in the case of dramatic weight loss
Diabetes, Obesity & Metabolism (PMID 29178519)
Jin et al
Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus
In biosimilars specifically, scale matters: the economics favor manufacturers capable of competing on both price and supply reliability simultaneously, because payers and PBMs will not accept single-source biosimilar supply after watching supply disruptions across the generic small-molecule market
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