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Safety and efficacy of GLP-1 receptor agonists in type 2 diabetes mellitus with advanced and end-stage kidney disease: A systematic review and meta-analysis
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Limitations Reflect Gaps in Ophthalmologic Monitoring The researchers acknowledged several study limitations, including substantial variability in assessment methods, the absence of a specific ICD-10 code for NAION, and the exclusion of participants with advanced diabetic eye disease, and stressed the need for additional research regarding the relationship between semaglutide and NAION The authors concluded, Treatment with semaglutide in adults was not associated with an increased risk of eye disorders or DR in this study, and future studies are unlikely to change these results
Other functions of GLP-1 include increased glucose uptake in the muscles, decreased glucose production in the liver, neuroprotection, and increased satiety due to direct actions on the hypothalamus
Liu W-L, Chang J-M, Chong I-W, Hung Y-L, Chen Y-H, Huang W-T, Kuo H-F, Hsieh C-C, Liu P-L
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