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Administration of -adrenergic receptor blockade reduces BAT 18F-FDG uptake (Soderlund et al., 2007) in patients with known or suspected cancer as well as in a patient with paraganglioma, a condition characterized by a massively increased metabolic BAT activity, induced by excess circulating catecholamines (Cheng et al., 2012)

Additionally, variations in the methodologies utilized to evaluate retinopathyranging from clinical assessments to imaging techniquescan lead to inconsistencies in the outcomes reported

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