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Therefore, this combination therapy, often described as pairing a liver-directed therapy (resmetirom) with a systemic metabolic agent (semaglutide), represents a promising, potentially more effective or optimal therapeutic approach than monotherapy in individuals with/without type 2 diabetes who have coexisting MASH [67,68,69]
In addition to avoiding potential issues like constipation, dry skin, or lightheadedness, adequate water intake is important because its associated with satiety and fullness as well
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