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Borghi L, Meschi T, Amato F, Briganti A, Novarini A, Giannini A
10.7150/ijbs.74304 51 WuY
This age-associated carnitine depletion contributes to mitochondrial dysfunction, reduced physical capacity, and metabolic inflexibility
This unexpected benefit prompted further research and ultimately led to the approval of GLP-1 drugs as effective treatments for obesity
however, individuals already taking glucose-lowering medicines (including insulin) may be at increased risk of hypoglycaemia if GH-mediated effects alter their insulin sensitivity Injection site reactions, including pain, redness, and infection risk For retatrutide , the side effect profile observed in clinical trials is consistent with that of other GLP-1 receptor agonists and includes nausea, vomiting, diarrhoea, and constipation
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