Compared to GIP, which has normal secretion but poor response in patients with T2D, GLP-1, which has low secretion but preserved response, is an important target in the development of antidiabetic drugs
Dai C, Walker JT, Shostak A et al (2020) Dapagliflozin does not directly affect human or cells
For most patients on a stable dose, the body handles this slight overlap without issue
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for them, FDA-approved alternatives like Oral Wegovy and Foundayo make practical sense