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Regulation of SIRT1 and its roles in inflammation

Elsevier Health Sciences

Animal studies at effective doses showed no overt toxicity, but this cannot be extrapolated to human safety

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Protocol Quick-Reference PRECLINICAL ONLY: NNMT inhibition research compound Dosing Amount No established human dose (mouse: ~34 mg/kg/day SC) Frequency No established human frequency Duration No established human duration Administration Route Oral Schedule N/A (preclinical compound) Timing NO HUMAN DOSING DATA EXISTS