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The PICALM/clathrin-dependent endocytosis mediates the internalization of the A-LRP1 complex in BECs

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In accordance with findings based on phase 3 semaglutide data investigating covariate effects on CL/ F [6], body weight was found to be the only important covariate with respect to CL and, hence, average semaglutide concentrations under steady-state conditions with 90% CIs outside the equivalence interval