What This Means Practically For someone weighing 220 pounds: On Trulicity (maximum dose): Expected loss: 7-11 pounds End weight: 209-213 pounds On Ozempic (maximum diabetes dose): Expected loss: 15-18 pounds End weight: 202-205 pounds On Wegovy (weight loss dose): Expected loss: 33 pounds End weight: 187 pounds The difference between Trulicity and higher-dose semaglutide is substantial for patients with significant weight to lose
Duration of diabetes and degree of beta-cell dysfunction also affect glycemic response, with longer disease duration sometimes associated with attenuated insulin secretory capacity
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