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Age-associated decline in SWS may account for frequent daytime lethargy and low energy levels [2]
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Drug development studies have utilized Angptl4 to determine whether small molecule LPL activators can enhance LPL activity and reverse Angptl4-mediated inhibition (78) were modified prior to docking so that they more closely represented the structures used in the experiments (i.e., LPL without the signal peptide, the region of ApoC-II covered by the synthetic peptide only, and the N-terminal fragment of Angptl4, respectively)
The NTD of GLP-1R is one of its key regions for ligand binding
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