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3.0 mL of bacteriostatic water gives a 3.33 mg/mL solution, so a 1 mg dose is 30 units on a U-100 insulin syringe and a 0.5 mg dose is 15 units

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The biomarker changes were shown to correspond with endpoints such as improved gait and body composition

According to NICE Clinical Knowledge Summaries, once B12 deficiency is adequately treated and symptoms resolve, routine monitoring of serum B12 levels is generally unnecessary, as clinical response is the primary indicator of treatment effectiveness

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