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Those on Certain Medications : Some medications, such as metformin (for diabetes) or proton pump inhibitors (for acid reflux), can interfere with B12 absorption

Because Vitamin B12 has a unique role in the production and regeneration of cells, this means that its important to have healthy levels of this vitamin to have healthy skin, hair and nails

Starting with lower doses and gradually increasing allows the body to adjust and reduces the likelihood of systemic reactions

Copper peptide results build progressively, and judging efficacy too early leads to unnecessary concentration escalation

These studies in mice evaluated dosing at an incredibly wide range (2.5-40mg/kg) with 5mg/kg being the median dose