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Transdermal estradiol had no effect

Buspirone Tablet Buspirone tablets are used to help relieve symptoms of anxiety such as worry, tension, and irritability

Slowing the ramp to the label cadence (2.5 mg start, 2.5 mg steps, four-week holds) dropped that to mid-single digits at every maintenance dose, at no cost to the 12-week result, and the dedicated slow-titration trial reached placebo range. Reaching 15 mg is not the problem