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doi:10.1016/j.rbmo.2018.10.008
Always use low-binding microcentrifuge tubes and pipette tips (siliconized or polypropylene) when handling dilute solutions below 10 mcg/mL, as surface adsorption can reduce effective concentrations by 20-50% in standard labware
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[135] Pediatric patients may require more frequent monitoring for adverse effects and dose adjustments based on clinical response
The compound remains detectable in urine for up to 4 days by mass spectrometry methods, despite its short plasma half-life, suggesting tissue distribution and binding may extend its biological effects beyond plasma clearance times
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